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Showing 10 out of 159 results
green circle with lungs
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Research Feature
Millions of people in America have been diagnosed with chronic obstructive pulmonary disease (COPD)—the umbrella term for emphysema and chronic bronchitis—and millions more have it and don’t know it. People in rural and other underserved communities are more likely to face higher rates of COPD and worse health outcomes from the disease. And for...
smiling young women wearing a mask in front of the strong heart banner.
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Research Feature
For 33 years, the NHLBI’s Strong Heart Study has focused on learning why American Indians have one of the highest heart disease rates in the nation—almost double that of the general population. And during that time, it has made important discoveries – confirming, for example, that risk factors like diabetes, high blood pressure, and elevated...
Medical lab test
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Research Feature
“Look at that! Life!” said Deidra Flowers-Williams, a sickle cell disease patient, as she held up a tube with stem cells donated by her sister, Tanisha Flowers. It was just minutes before doctors at the NIH Clinical Center would use the cells – extracted from her sister’s bone marrow – for a transplant they hoped would cure the devastating blood...
Technician operates Gazelle platform, a portable lab-on-a-chip device that can identify sickle cell disease from a blood droplet. Photo source: Hemex Health
Credit: Hemex Health
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Research Feature
About 20 years ago, researchers excitedly announced the coming of so-called lab-on-chip devices that could revolutionize medicine. At the time, people marveled at the possibilities: The devices would take the capabilities of a large biochemistry lab and shrink them to a platform the size of a cell phone or smaller. With help from a portable scanner...
Female scientist looking into a microscope
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Research Feature
When COVID-19 restrictions closed research laboratories across the country, it meant Erik Kimble, M.D.’s hematology and oncology training came to a virtual crawl. Not surprisingly, Kimble, who completed medical school in Mexico at the height of the swine flu pandemic, was overwhelmed yet again with uncertainty. He spent months preparing for his...
Correlative light and electron microscopy image of the protein dynamin (magenta) at endocytic structures (grey honeycomb lattice) of a mammalian cell.
Credit: Kem Sochacki, Ph.D. NHLBI, DIR
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Research Feature
Every day researchers across NIH use an array of imaging technologies and equipment to help them make new scientific discoveries. However, over the last 10-15 years, a massive explosion in the use of Cryo-Electron Microscopy (cryo-EM) – a technique that allows the direct imaging of proteins within cells – has revolutionized the way scientists do...
Doctors evaluate older man hospitalized with COVID-19
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Research Feature
For nearly 15 years, the Cardiothoracic Surgical Trials Network (CTSN) has played a key role in designing and conducting collaborative clinical trials aimed at improving surgical treatments for cardiovascular disease, the nation’s leading cause of death. CTSN’s efforts to learn more about these treatments – valve replacements, bypass procedures...
A physician talks to a young patient in a medical exam room.
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Research Feature
At St. Louis Children’s Hospital in Missouri, a 12-year-old boy waiting in an exam room held a tablet as he scrolled through a trivia game about sickle cell disease (SCD) – an inherited blood disorder that had brought him to the hospital for a regular visit. As he played the game, he won a badge each time he answered a question right. But happily...
Intra Operative photo of Dr. Singhal M.D.
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Research Feature
Lymphedema is a potentially debilitating condition affecting more than 1 million people in the U.S. each year. Its main symptom is swelling of the arms or legs, but if left untreated, lymphedema can lead to severe discomfort and life-threatening infections. The swelling associated with the disease is caused by a failure of the lymphatic system, a...
Senior Asian woman experiences leg pain while in bed.
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Research Feature
It’s been called the most common disease nobody’s heard of – and also one of the big mysteries in medicine. It’s restless legs syndrome (RLS), a neurological and sleep disorder that causes discomfort and sometimes pain in the legs, particularly at night. It triggers a constant urge to move the legs that makes falling asleep and staying asleep...