NEWS & EVENTS
Sickle Cell In Focus Conference 2018 Logo

Sickle Cell in Focus Conference 2018

October 22 - 23 , 2018
Natcher Conference Center, Ruth L. Kirschstein Auditorium
45 Center Dr., NIH, Bethesda, MD 20894

Description

After an exciting event in Kingston, Jamaica in October 2017, we are thrilled to announce that the 12th annual Sickle Cell in Focus (SCiF) conference will return to the National Institutes of Health (NIH) on October 22-23, 2018.

SCiF is a two-day, intensive, educational update on sickle cell disease. This year’s conference will focus on management of the older adult patients, curative therapies, systems medicine, and will also include 2 debates on issues for which there are no clear answers.

This comprehensive and global exploration of the current medical trends and research results in sickle cell disease and thalassemia is geared towards consultants, trainees, doctors, healthcare professionals, and academics interested in hemoglobin disorders.

Watch Live:

October 22: https://videocast.nih.gov/live.asp?live=28814

October 23: https://videocast.nih.gov/live.asp?live=28818

 

To view the complete Event Program click here.

For inquiries regarding CE credits, please contact SCiFConference@nhlbi.nih.gov

Read more

Agenda

8:00am
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Registration

9:00am
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Opening Remarks

Richard Childs
Clinical Director, National Heart, Lung, and Blood Institute

9:05am - 10:05am
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SESSION ONE: Sickle Cell Disease in 2018

Chairs: Vence Bonham / Jennifer Knight-Madden

9:05am - From birth to adults, has survival improved?
Kathryn Hassell
University of Colorado School of Medicine, Aurora, CO, USA

Optimizing current approved therapies

9:35am - Implementation research: Improving coverage of patients taking HU
Keith Hoots
National Institutes of Health, Bethesda, MD, USA

10:05am - Translating Clinical Care to Developing Countries
Russell Ware
Cincinnati Children’s Hospital Medicine Center, Cincinnati, OH, USA

10:35am
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BREAK

10:45am - 11:45am
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SESSION TWO: SCD in Adults

Chairs: Oswaldo Castro / Laura de Castro

10:45am - Optimal disease management & health monitoring in older adults
Sophie Lanzkron
John Hopkins Medicine, Baltimore, MD, USA

11:15am - How we manage VTE’s in adults
Theodore Wun
UC Davis Comprehensive Cancer Center, Sacramento, CA, USA

11:45am - Understanding pain and its mechanisms
Catherine Bushnell
National Institutes of Health, Bethesda, MD, USA

12:15pm
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LUNCH

1:15pm - 1:45pm
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SESSION TWO: SCD in Adults (cont.)

Chairs: Oswaldo Castro / Laura de Castro

1:15pm - The many facets of sickle pain and its management
Samir Ballas
Thomas Jefferson University, Philadelphia, PA

1:45pm - Management of liver complications in SCD
Abid Suddle
King’s College Hospital NHS Foundation Trust, London, UK

2:15pm - 3:15pm
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SESSION THREE: Blood transfusion and iron overload

Chair: Patricia Shi

2:15pm - Presentation of the untransfusable patient
Arun Shet
National Institutes of Health, Bethesda, MD

2:45pm - Genotyping vs extended phenotyping
Connie Westhoff
New York Blood Center, New York, NY, USA

3:15pm - Iron overload in SCD, are we making progress?
John Porter
University College Hospital, London, UK

3:45pm
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BREAK

4:00pm - 4:40pm
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DEBATE 1: Biomarkers in SCD: Just a lot of noise and handwaving

Chair: Patricia Oneal

4:00pm - Pro: David Rees
King’s College London, London, UK

4:20pm - Con: Marilyn Telen
Duke School of Medicine, Durham, NC, USA

4:40pm - Debate

5:00pm
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DAY ONE CLOSE

7:30am
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Registration

8:30am
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Opening Remarks

Gary H. Gibbons
Director, National Heart, Lung, and Blood Institute, Bethesda, MD, USA

8:35am - 10:05am
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SESSION FOUR: Unanswered questions and new frontiers in curative therapies

Chair: Allistair Abraham

8:35am - Allo-HSCT: match related, match unrelated, cord blood, and haplo
Mark Walters
Children's Hospital Oakland Research Institute, Oakland, CA

9:05am - Collecting HSCs, not a trivial business
John Tisdale
National Institutes of Health, Bethesda, MD, USA

9:35am - Gene therapy-addition, correction
Dan Bauer
Boston Children’s Hospital, Boston, MA, USA

10:05am - Update on gene addition therapy in SCD
Alexis Thompson
Northwestern University, Chicago, IL, USA

10:35am
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BREAK

10:45am - 11:45am
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SESSION FIVE: Cerebrovascular disease in SCD

Chair: Eboni Lance

10:45am - Cerebrovascular disease in SCD: In Children
Lori Jordan
Vanderbilt University Medical Center, Nashville, TN, USA

11:15am - Neurocognitive outcomes in SCD
Allison King
Washington University in St. Louis, St. Louis, MO, USA

11:45am - Cerebral Hemodynamics in sickle cell disease and sickle cell carriers
Monica Hulbert
St. Louis Children’s Hospital, St. Louis, MO, USA

12:15pm
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LUNCH

1:15pm - 1:45pm
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SESSION SIX: Inflammation and vascular injury in SCD

Chair: Hans Ackerman

1:15pm - The common ground between SCD and Malaria
Tom Williams
KEMRI/Wellcome Trust Research Programme, Kilifi, Kenya

1:45pm - Elevated inflammatory markers - Do they mean anything in sickle pathophysiology?
Nicola Conran
University of Campinas, Sao Paulo, Brazil

2:15pm - 3:15pm
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SESSION SEVEN: System medicine and Big Data: Transforming care of SCD to the 21st century

Chair: Suvanka Majumdar

2:15pm - Complex genetics for a simple mutation-getting to the heart of the matter
Swee Lay Thein
National Institutes of Health, Bethesda, MD, USA

2:45pm - A short cut to modeling SCD
George Karniadakis
Brown University, Providence, RI, USA

3:15pm - Machine Learning to predict cardiovascular phenotypes of SCD
Vandana Sachdev
National Institutes of Health, Bethesda, MD, USA

3:45pm
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BREAK

4:00pm - 4:40pm
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DEBATE 2: Developing therapies for SCD - Makes more sense to target the root cause than all the downstream events

Chair: Robert Nickel

4:00pm - Pro: Yogen Saunthararajah
Cleveland Clinic, Cleveland, OH, USA

4:20pm - Con: Jane Little
UH Cleveland Medical Center, Cleveland, OH, USA

4:40pm - Debate

5:00pm
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CLOSE OF CONFERENCE