Bethesda, MD 20892
Description
Recent advances in omic tools-(genomics, proteomics, transcriptomics and metabolomics and their critical metabolites)-have created a set of tools box that can use small blood volumes for ultra- sensitive detection of key biomarkers that will allow creation of pathophysiological molecular finger prints. This will be an easy, fast, inexpensive and sensitive tool for disease diagnostic and prediction on a Nano scale. One can use blood diseases as pilots to explore such technologies. How early can the technology enable detect and predict (for example), early onset stroke, pulmonary hypertension or a vasculopathy in SCD-Sickle cell disease or in certain BMFS-Bone marrow failure disorders, be able to predict early onset of cancers (common in these disorders) and stroke in a thrombotic event. Although the proof of concept for the technology has been shown to be available, there is an unmet need for early diagnosis. This workshop will help explore further the technologies required for creation of key markers and molecular fingerprints for an early detection.
Contact
Pankaj Qasba, Ph.D.
Program Director,
Blood Diseases Branch Division of Blood Diseases and Resources
6701 Rockledge Dr, MSC 7950
Bethesda, MD 20892-7950
301-435-0070, Fax:301-480-0867
E-mail: qasbap@nhlbi.nih.gov